DNA Algorithms

Shareable algorithm concepts focused on genome maintenance and longevity.

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APR-Router (AHR–PARP1 Repair Routing)

Treat tissue aging as a control system. Route interventions through AHR activation → PARP1 dynamics → barrier integrity → inflammation feedback, optimizing genome maintenance signals without drifting into inflammatory collapse.

Inputs

IAA / tryptophan-metabolite spectrumAHR activity proxiesDNA damage markers (γH2AX, comet, etc.)Barrier integrity proxiesInflammatory cytokine panel

Outputs

Intervention schedule (pulsed metabolite + diet substrate)
Risk score for genome instability drift

Constraints

No personal medical advice
Avoid unsafe claims; prefer mechanistic + evidence-linked statements

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Patchwise Drift Controller (PDC)

Model tissue as mosaic clonal patches; optimize to minimize drift variance (patchiness) plus mean drift while bounding proliferative risk.

Inputs

clonal-unit drift vectorsepigenetic clocksinflammation state

Outputs

targeted patch intervention plan
monitoring cadence

Constraints

avoid oncogenic regime activation
prefer reversible modulation